Evolução do gene sodC nas bactérias naturalmente transformáveis Neisseria meningitidis e Haemophilus influenzae

TL;DRAbstract

In 1998, it was reported the lateral transfer of the sodC gene from the genus Haemophilus to Neisseria meningitidis. It is known that this two groups show a quite distinct dynamics of this gene. This study aims to estimate phylogenetic trees that migh tpoint to which species of the genus Haemophilus shared the sodC gene with N. meningitidis. In addition, tests of positive selection were employed in order to assess which evolutionary forces are governing the process of molecular diversification of the gene in these species through time. Moreover, we performed a computational protein modeling by homology to asses which amino acids substitutions had an impact on the adaptative process of the enzyme in the species considered. A phylogeny of the sodC gene was reconstructed and it was found that this gene in H. influenzae has two different origins.A group of lineages has received the gene, probably by lateral transfer, from H. haemolyticus, whereas the other group has received the gene from

Chat with Paper

AI Agents for this Paper