Pathology of Fibrocystic Diseases of the Liver

TL;DRAbstract

Fibrocystic liver diseases may occur in isolation or present as autosomal dominant or recessive polycystic disease. Abnormal embryologic development of the ductal plates is thought to be the common underlying cause of this diverse group of hepatic and biliary tract lesions. They also share common histopathological features including intrahepatic bile ductal dilatation and hepatic fibrosis of various degrees. These lesions can be clinically silent or lead to clinically obvious symptoms and signs. The pathology of these lesions is discussed in this chapter.

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