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Pharmacological Effects of Propylthiouracil on Corticosterone Secretion in Male Rats

Ming Jae Lo,Shyi Wu Wang,Mei Mei Kau,Jiann Jong Chen,Yen Hao Chen,V. S. Fang+2 more-1998-12-01-Journal of Investigative Medicine
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TL;DRAbstract

These results suggest that PTU counteracts both basal and ACTH-induced adrenal steroidogenesis through their attenuation of the activity of 11 beta-hydroxylase and cAMP production in rat ZFR cells.

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These results suggest that PTU counteracts both basal and ACTH-induced adrenal steroidogenesis through their attenuation of the activity of 11 beta-hydroxylase and cAMP production in rat ZFR cells.

Keywords

Internal medicineEndocrinologyCorticosteronePropylthiouracilForskolinChemistryCyclic adenosine monophosphateAdrenocorticotropic hormone

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