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Open AccessArticle10.1016/j.bmcl.2015.07.037

Discovery of Tyk2 inhibitors via the virtual site-directed fragment-based drug design

Woo Dae Jang,Jun-Tae Kim,Hoon Young Son,Seung Yeon Park,Young Sik Cho,Tae‐Sung Koo+2 more-2015-07-21-Bioorganic & Medicinal Chemistry Letters
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Keywords

Tyrosine kinase 2ChemistryPhosphorylationKinaseSignal transductionReceptorTyrosine phosphorylationDrug discovery

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