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[Characterization of pseudotyped viruses coated with hemagglutinin of H5N1 avian influenza].

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TL;DRAbstract

Pseudotyped Viruses coated with HA of H5N1 High Pathogenic Avian Influenza were successfully constructed; it can be used to for the microneutralization assay. The HA gene from different sources affect the efficiency of the packaging of the pseudovirus. But the optimized HA gene can not obviously improve packaging efficiency of the pseudovirus.

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Pseudotyped Viruses coated with HA of H5N1 High Pathogenic Avian Influenza were successfully constructed; it can be used to for the microneutralization assay. The HA gene from different sources affect the efficiency of the packaging of the pseudovirus. But the optimized HA gene can not obviously improve packaging efficiency of the pseudovirus.

Keywords

VirologyInfluenza A virus subtype H5N1VirusBiologyHemagglutinin (influenza)Neutralization

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