Evaluation of PET-MRI fusion for the detection of NET liver metastases

TL;DRAbstract

564 Objectives To assess the impact of PET-MRI fusion on the detection of liver metastases of neuroendocrine tumors (NET) in comparison to NET-specific Ga-68-DOTATOC PET/CT and liver-specific Gd-EOB-DTPA MRI. Methods 22 consecutive patients with suspicious liver metastases from histopathologically proven NET were examined with Gd-EOB-DTPA MRI and multiphase contrast-enhanced Ga-68-DOTATOC PET/CT within a maximum time of 6 days between investigations. PET and MRI images were retrospectively fused with e.soft4.0m (Siemens). PET/CT, MRI and PET-MRI fusion images were evaluated by 2 physicians experienced in nuclear medicine and radiology with a time interval of 6 weeks between the reading of each modality. A 5-point and 3-point visual scoring system were used to assess confidence level and dignity of liver lesions, respectively. The reference standard of each lesion was histopathology and/or follow-up examinations of at least six months. To determine the diagnostic performance, ROC analys

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