Explore the dynamic alternation of gene PLAC4 mRNA expression levels in maternal plasma in second trimester for nonivasive detection of trisomy 21
Lan Yang,Hai-Yan Sun,Dao-Zhen Chen,Mu-Dan Lu,Ye Tang,Jian-Pin Xiao-2015-01-01-Obstetrics & Gynecology Science
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TL;DRAbstract
The PLAC4 mRNA showed a higher level of expression in the gestation of 18 to 21 weeks with an euploid pregnancy of pregnant women. We also found that there was no significant difference in plasma PLAC4 mRNA concentration between the normal and the T21 pregnancies in second trimester.
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The PLAC4 mRNA showed a higher level of expression in the gestation of 18 to 21 weeks with an euploid pregnancy of pregnant women. We also found that there was no significant difference in plasma PLAC4 mRNA concentration between the normal and the T21 pregnancies in second trimester.
Keywords
TrisomyAndrologyGeneMessenger RNAGene expressionReal-time polymerase chain reactionSecond trimesterBiology
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