Autonomic control mechanisms in the brush possum (Trichosorus vulpecula).

TL;DRAbstract

The autonomic influences on some organ systems in the possum (Trichosurus vulpecula) have been studied. The work has also included aspects of possible mechanisms for the modulation of autonomic function by endogenous prostaglandins and lipids. Noradrenaline has been identified by pharmacological methods. The chemical method used was not sensitive enough to identify noradrenaline positively in the splenic tissue and in the venous effluent of the electrically stimulated spleen. Support for noradrenaline being the neurotransmitter at sympathetic nerve endings comes from indirect evidence. Phenoxybenzamine blocks the effect of sympathetic nerve stimulation in the hind limb vascular bed. Phentolamine blocks the contracture of the nictitating membrane when the preganglionic nerve is stimulated and it also blocks part of the effect induced by sympathetic nerve stimulation of the possum gut. Propranolol blocks a component of the reflex changes in heart rate induced by a variety of methods. Les

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