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Efficacy of transarterial chemoembolization prior to liver transplantation for hepatocellular carcinoma as found in pathology.

Georgios C. Sotiropoulos,Massimo Malagó,Ernesto P. Molmenti,Andreas Paul,Silvio Nadalin,Eirini I. Brokalaki+5 more-2005-07-12-PubMed
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TL;DRAbstract

Our data show that TACE provides acceptable local tumor control as bridging treatment before liver transplantation. Although the majority of our patients (15/21, 71.4%) had 2 or more tumor lesions at the beginning of treatment, tumor progression was observed in only a minority (14.3%) of patients. However, multifocal tumors could not be successfully under-staged through this treatment and, furthermore, vital tumor was always observed in pathology; the usefulness of TACE in multifocal disease has to be re-estimated.

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Our data show that TACE provides acceptable local tumor control as bridging treatment before liver transplantation. Although the majority of our patients (15/21, 71.4%) had 2 or more tumor lesions at the beginning of treatment, tumor progression was observed in only a minority (14.3%) of patients. However, multifocal tumors could not be successfully under-staged through this treatment and, furthermore, vital tumor was always observed in pathology; the usefulness of TACE in multifocal disease has to be re-estimated.

Keywords

Hepatocellular carcinomaMedicinePathologicalLiver transplantationCirrhosisTumor progressionTransplantationLiver tumor

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