Stimulant treatment and the mixed ADHD/CD subtype : an investigation of acute effects in a sample of adolescent offenders
TL;DRAbstract
Previous research invest,igating paramet.ers of Abtention Deficit Hyperactivity Disorder (ADHD), including response t.o stimulant drug t.reatment, has typically failed to control for associated conduct symptomatology, thereby preventing delineation of potentially imporbant subgroup responses. In view of both the markedly high conlorbidiby of Conduct Disorder (CD) with ADHD and empirical robust, indications of a chronic poor prognosis for this subgroup, a need for the evaluation of specific interventions for t.he mixed ADHD/CD subtype has been voiced. To date, the short-term effect,s of psychoact.ive drug t.reatment have not been researched in mixed ADHDICD adolescent groups. The present study investigated the acute effects of a 10-day, briple-blind, within-subject t,rial of placebo and two doses of met,hylphenidate (MPH) on ADHD symptomatology in a subgroup of male, adolescent, inpabient offenders who met t,he combined DSM-I11 diagnostic crit.eria for ADDH and CD. Thirty-bhree youths,
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Previous research invest,igating paramet.ers of Abtention Deficit Hyperactivity Disorder (ADHD), including response t.o stimulant drug t.reatment, has typically failed to control for associated conduct symptomatology, thereby preventing delineation of potentially imporbant subgroup responses. In view of both the markedly high conlorbidiby of Conduct Disorder (CD) with ADHD and empirical robust, indications of a chronic poor prognosis for this subgroup, a need for the evaluation of specific interventions for t.he mixed ADHD/CD subtype has been voiced. To date, the short-term effect,s of psychoact.ive drug t.reatment have not been researched in mixed ADHDICD adolescent groups. The present study investigated the acute effects of a 10-day, briple-blind, within-subject t,rial of placebo and two doses of met,hylphenidate (MPH) on ADHD symptomatology in a subgroup of male, adolescent, inpabient offenders who met t,he combined DSM-I11 diagnostic crit.eria for ADDH and CD. Thirty-bhree youths,
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