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Immunomodulatory effects of HBsAg vaccine and levamisole in chronic hepatitis B and hepatitis B carrier children.

Fikret Demirci,Ziya Bayraktaroǧlu,Murat Karaoğlan,Yavuz Çoşkun,İlkay Karaoğlan,Vahap Okan-2005-12-01-PubMed
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TL;DRAbstract

It was found that HBsAg vaccine induced cellular immunostimulation in children with chronic hepatitis B; however, levamisole did not. The immune cells of hepatitis B carriers did not manifest a significant change in any treatment group. Although there was no change in B-cell, significant decreases were determined in immunoglobulins (IgG, IgA), especially in chronic hepatitis B patients.

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It was found that HBsAg vaccine induced cellular immunostimulation in children with chronic hepatitis B; however, levamisole did not. The immune cells of hepatitis B carriers did not manifest a significant change in any treatment group. Although there was no change in B-cell, significant decreases were determined in immunoglobulins (IgG, IgA), especially in chronic hepatitis B patients.

Keywords

MedicineLevamisoleHBsAgHepatitis B vaccineHBeAgImmunologyHepatitis BAntibody

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