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Neurovegetative Criteria for Evaluation of Cerebral Circulation Recovery of the Resuscitated Organism

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Objective: to assess the diagnostic informative value of some neurovegetative parameters as criteria for evaluating the adequacy of cerebral circulatory recovery at the early stage of resuscitation. Materials and methods. Experiments were performed on 65 cats under anesthesia with nembutal, 45 mg/kg intraperitoneally. A model of 5-minute clinical death from prolonged blood loss (50 mm Hg, a Wiggers hemobarostat) was employed. Cerebral circulation (hydrogen clearance), cardiac output, and its distribution (thermodilution) were recorded. The autonomic indices, such as the Kerdo, Algover, Robinson, and Hilebrant ones, were calculated. An index of regulatory system tension was estimated (analysis of cardiac rhythm variability). Results. There was a close, direct correlation of postresuscitative changes in cerebral circulation with cardiac output and its redistribution. The phasic pattern of cerebral circulatory recovery is reflected by the time course of changes in the neurovegetative indi

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Objective: to assess the diagnostic informative value of some neurovegetative parameters as criteria for evaluating the adequacy of cerebral circulatory recovery at the early stage of resuscitation. Materials and methods. Experiments were performed on 65 cats under anesthesia with nembutal, 45 mg/kg intraperitoneally. A model of 5-minute clinical death from prolonged blood loss (50 mm Hg, a Wiggers hemobarostat) was employed. Cerebral circulation (hydrogen clearance), cardiac output, and its distribution (thermodilution) were recorded. The autonomic indices, such as the Kerdo, Algover, Robinson, and Hilebrant ones, were calculated. An index of regulatory system tension was estimated (analysis of cardiac rhythm variability). Results. There was a close, direct correlation of postresuscitative changes in cerebral circulation with cardiac output and its redistribution. The phasic pattern of cerebral circulatory recovery is reflected by the time course of changes in the neurovegetative indi

Keywords

MedicineCerebral circulationCardiac outputCirculatory systemCerebral blood flowCardiac indexPerfusionAnesthesia

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