Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O <sub>2</sub> -Regulated Prolyl Hydroxylation
2001 · Science · 5,454 citations
https://doi.org/10.1126/science.1059796
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Patrick H. Maxwell
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Patrick H. Maxwell is an academic researcher from University of Cambridge. The author has contributed to research in topics: Cancer, Hypoxia, and Metabolism & High Altitude and Hypoxia & Epigenetics and DNA Methylation. The author has an h-index of 95, co-authored 323 publications.
ORCID: 0000-0002-0338-2679Papers by this author
worksC. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
2001 · Cell · 3,325 citations
https://doi.org/10.1016/s0092-8674(01)00507-4
Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays
2022 · Cell · 1,569 citations
https://doi.org/10.1016/j.cell.2022.04.003
Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity
2022 · Nature · 1,137 citations
https://doi.org/10.1038/s41586-022-04474-x
Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein
2000 · Journal of Biological Chemistry · 1,042 citations
https://doi.org/10.1074/jbc.m002740200
Contrasting Properties of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-Associated Renal Cell Carcinoma
2005 · Molecular and Cellular Biology · 929 citations
https://doi.org/10.1128/mcb.25.13.5675-5686.2005
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