Coexpression profile of leukemic stem cell markers for combinatorial targeted therapy in AML
2018 · Leukemia · 311 citations
https://doi.org/10.1038/s41375-018-0180-3
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Klaus H. Metzeler
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Klaus H. Metzeler is an academic researcher from University Hospital Leipzig. The author has contributed to research in topics: Acute Myeloid Leukemia Research & Myeloproliferative Neoplasms: Diagnosis and Treatment & Cancer Genomics and Diagnostics. The author has an h-index of 56, co-authored 368 publications.
ORCID: 0000-0003-3920-7490Papers by this author
worksBlockade of the PD-1/PD-L1 axis augments lysis of AML cells by the CD33/CD3 BiTE antibody construct AMG 330: reversing a T-cell-induced immune escape mechanism
2015 · Leukemia · 239 citations
https://doi.org/10.1038/leu.2015.214
FLT3 internal tandem duplication associates with adverse outcome and gene- and microRNA-expression signatures in patients 60 years of age or older with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study
2010 · Blood · 230 citations
https://doi.org/10.1182/blood-2010-05-283648
Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia
2018 · Leukemia · 137 citations
https://doi.org/10.1038/s41375-018-0034-z
Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia
2013 · Blood · 86 citations
https://doi.org/10.1182/blood-2012-07-446120
Tyrosine kinase inhibition increases the cell surface localization of FLT3-ITD and enhances FLT3-directed immunotherapy of acute myeloid leukemia
2017 · Leukemia · 85 citations
https://doi.org/10.1038/leu.2017.257
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